What are non-urothelial cell bladder cancers? These are a small subset of bladder cancers that, confusingly, often arise from the urothelium, and include squamous cell carcinomas and adenocarcinomas.

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Bladder cancer is the sixth most common cancer in the United States but it is rarely talked about. Tune in as urologist, Ramdev Konijeti, MD, discusses the symptoms of bladder cancer and available treatments, including immunotherapy, on KUSI. Learn more: http://bit.ly/Bldcyt

When Dave was diagnosed with bladder cancer in 2008, he knew nothing about the disease or its signs and symptoms. Hoping to raise awareness about bladder cancer, Dave and his wife Maureen share their story about learning to spot the disease’s symptoms, being diagnosed and living with the disease.

To learn more about bladder cancer and the symptoms that mean you should take early action (e.g., blood in your urine that’s red or brown in colour), visit www.wecarecampaign.org and sign up for the We Care pledge.

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Ebony was 45 when she first noticed blood in her urine. But after different scans and scopes, doctors couldn’t find anything. They initially thought it was a UTI. After more than year, she was diagnosed with stage N2 bladder cancer.

She then underwent MVAC chemotherapy and an 8-hour surgery to remove her bladder. As part of this surgery, part of Ebony’s small intestines were used to create a neobladder.

In this conversation she shares her cancer journey, including taking control of her hair loss, the importance of self-advocacy and support and using her story to be a light for others.

Full story & transcript → https://www.thepatientstory.com/patient-stories/bladder-cancer/ebony-g/
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Highlighting key topics in cancer surveillance, this video from the National Cancer Institute (NCI) looks at bladder cancer trends in the United States.

Here is NCI’s information on bladder cancer: www.cancer.gov/bladder
Find more cancer statistics from NCI’s Surveillance, Epidemiology, and End Results (SEER) Program: http://www.seer.cancer.gov
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Dr. Inderbir Gill, Founding Executive Director of the USC Institute of Urology, answers questions about bladder cancer.

For more information, visit:
http://urology.keckmedicine.org
or call (323) 442-4827.

Music:
“”Mining by Moonlight”” Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0
http://creativecommons.org/licenses/by/3.0/”
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R. Jeffrey Karnes, M.D., Consultant and Associate Professor, Mayo Clinic, discusses treatment options for bladder cancer. The ailment can be subdivided into sub categories and the treatments dramatically differ. Invasive treatments can include an ileal neobladder created from the patient’s small intestine can provide the best quality of life.
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Bladder cancer is the 5th most common cancer and is much more common in smokers. UCSF genitourinary cancer specialist Dr. Terence Friedlander reviews the basic biology and pathophysiology of bladder cancer, focusing on methods used to detect bladder cancer, treatment of early-stage disease with therapies administered into the bladder, the role of surgery or radiation therapy in the treatment localized disease, the role of chemotherapy for metastatic disease, and new directions in the field, particularly the role of immunotherapy in bladder cancer. Recorded on 06/24/2014. [9/2014] [Show ID: 28499]

Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date.

More from: The Ins and Outs of Genitourinary Cancer
(https://www.uctv.tv/series/794)

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Dan Reznicek MD, a Urologist in Bellingham Washington, covers the basics of bladder cancer. Bladder cancer is common and is one of the top 5 cancers diagnosed every year in the US. In addition to this video, see resources available at www.nccn.org, www.bcan.org, and visit our website at www.pacificnorthwesturology.com.

Basics:
What is bladder cancer?
How does bladder cancer happen?
What are the symptoms?
What is the workup?
How is it treated?

What is bladder cancer?
Bladder cancer is a the development of a group of cells in the lining of the bladder that begin to grow and divide uncontrollably. They are in the urothelium of the bladder.

What is the urothelium
This layer prevents you from reabsorbing the salts in the urine and the waste products that have been excreted. It is also a barrier from bacteria and infection.

The vast majority of bladder cancers in this country come from the lining of the urothelium and are known as urothelial carcinoma. Historically, it was also called transitional carcinoma.
The other bladder cancers that will not be covered in this video are small cell carcinoma, adenocarcinoma, and squamous cell carcinoma. These are quite rare, and their outcomes and treatments are different from urothelial carcinoma.

Risk factors include smoking, male sex, and exposures to certain chemicals used in the dye and textile industry.

What are symptoms of bladder cancer?

Most people are diagnosed with bladder cancer after seeing blood in the urine (also called hematuria). Sometimes your urine may look normal, but blood is seen on a urine test at your doctor’s office and that is called microscopic hematuria. See a doctor if you note blood in your urine.

Usually there is no pain with bladder cancer in early stages. In some people, they can develop irritative voiding symptoms such as burning with urination, more frequent urination, difficulty urinating or a weak stream, and the sudden urge to urinate. These symptoms will seem like a urinary tract infection but no bacteria is seen on a culture. These symptoms are less common but can occur.

If bladder cancer is caught late and spread to other areas of the body, patients may experience back pain, weight loss, tiredness, swelling, bone pain, and other symptoms.

What is the workup?

A medical history and perform a physical exam. Other tests that may be performed include urine tests with a culture, cancer markers, or microscopic exam. Imaging tests such as a CT scan, Ultrasound, or MRI may be recommended. A cystoscopy should be performed if bladder cancer is suspected or possible.

How is it treated?
Treatment depends on the stage of the cancer. TNM staging of bladder cancer is covered in the video.

Cancers that are in the lining of the bladder alone are known as non-muscle invasive bladder cancer (NMIBC). These are treated with endoscopic removal (transurethral resection of a bladder tumor [TURBT]) and may require further local therapies with drugs instilled into the bladder.

Some cancers involve the muscle of the bladder and require further treatment. Muscle invasive bladder cancer is treated with surgery, chemoradiation, or a combination of therapies. If left untreated, muscle invasive bladder cancer can be deadly and we highly recommend treatment.

Metastatic cancer is less common and describes bladder cancer that has spread beyond the bladder and into other organs. 4% of cancers are diagnosed at this stage. At this point in time, metastatic bladder cancer is incurable, but new treatments are being discovered each year. Treatments at this stage are focused on slowing the cancer growth and lengthening survival.

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For George Furlan, blood in the urine turned into a worse case scenario.

“Within 10 days he found some cancer and a tumor in my bladder,” says George Furlan,.

There was a silver lining to his bladder cancer. It was caught at an early stage when it’s most treatable, says Furlan’s doctor Alejandro Miranda-Sousa, urologist on Lee Memorial Health System’s medical staff.

“Correct. Usually the low- grade cancer, the scrapping or removal of the tumor is done with no cuts all. Sometimes medication is given within the bladder; a form of chemotherapy or immunotherapy could be given to treat and prevent recurrences,” says Dr. Miranda-Sousa.

Low- grade tumors, like Furlan’s, can present like cauliflower with roots that grow into the bladder lining. In this instance, treatment included both the removal and chemotherapy.

“He said to me you’re doing fine but I have to cut one of the tumor and I left some of the roots which did not penetrate the wall yet. I want to take care of that by giving you my treatment for 6 weeks,” says Furlan.

Bladder cancer tends to recur; close to 50% of patients will battle it again.

“The follow up is to check the bladder every 3 months for the first 2 years after the tumor has been discovered. Many tumors come back as low a grade. Those are much more simple to treat and have a high rate of curing,” says Dr. Alejandro Mirando-Sousa.

When the cancer is caught early, the outlook is good. If it’s diagnosed in situ, meaning the layer of cells it where it began, patients have a 97% 5-year survival rate. If it’s stage 1- the rate is 70%. Patients with stage IV bladder cancer are rarely cured, making it important to check out any symptoms.

“Blood in the urine is most common, but obviously urgency, frequency, going to the bathroom very often at night, changes in the flow of urination. The most important thing I recommend to patients is periodically visit your doctor,” says Dr. Miranda-Sousa.

The vigilance paid off for Furlan.

“Everything was fine, the tumor completely disappear,” says Furlan.

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Lee Memorial Health System in Fort Myers, FL is the largest network of medical care facilities in Southwest Florida and is highly respected for its expertise, innovation and quality of care. For nearly a century, we’ve been providing our community with everything from primary care treatment to highly specialized care services and robotic assisted surgeries.

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There are several types of bladder cancer, and treatment depends on where the cancer began and the stage of disease. In this video, Dr. Petros Grivas and Dr. Jonathan Wright discuss what people diagnosed with bladder cancer should know, including questions to ask their doctor, current treatment options, and the latest research in bladder cancer.

More Information
Bladder Cancer
https://www.cancer.net/cancer-types/bladder-cancer

ASCO Answers Fact Sheet: Bladder Cancer (PDF; 2 pages) https://www.cancer.net/sites/cancer.net/files/asco_answers_bladder.pdf

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Learning about bladder cancer can be intimidating. Mark Tyson, M.D., a urologist at Mayo Clinic, walks you through the facts, the questions, and the answers to help you better understand this condition. For more reading visit: https://mayocl.in/3vcSF5u. When it comes to your health, Mayo Clinic believes credible and clear information is paramount. There’s a lot to learn about bladder cancer. We’re here to help.

0:00 Introduction
0:37 What is bladder cancer?
0:53 Who gets bladder cancer? / Risk factors
1:32 Symptoms of bladder cancer
1:59 How is bladder cancer diagnosed?
2:39 Treatment options
3:25 Coping methods/ What now?
4:04 Ending

Still have questions about bladder cancer? That’s okay. https://www.youtube.com/watch?v=71F7LcCitBo

More videos on bladder cancer Mayo Clinic Q&A podcast: Bladder cancer patients require ongoing surveillance

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